PyRosetta is available for Mac (64-bit OS X v10.5+) and Linux (64-bit Red Hat and 64-bit Ubuntu) platforms in continuous release versions (usually we have a fresh builds available daily). Running on Windows-10 (thought Unix layer) is are also supported. Additionally, both Python 2.7 and 3.5 is supported.
A Rosetta license is required in order to download and use PyRosetta. Licensing is free for academic and non-profit institutions and is available to commercial users for a fee. Academic and commercial licensing of PyRosetta is handled with the standard Rosetta license through Rosetta Commons. Please click here for more information.
Speed optimized build, use it for production runs on system with no memory constraints.
Build optimized to reduce memory footprint. Use this build with low-memory systems.
Binaries compiled in debug mode with additional asserts enabled and with debug-info compiled-in. Use this to build for debugging.
On CentOS and on Ubuntu Linux we provide binaries for both Python-2.7 and Python-3.5.
[Python-2.7.Release] [Python-2.7.MinSizeRel] [Python-2.7.Debug]
[Python-3.5.Release] [Python-3.5.MinSizeRel] [Python-3.5.Debug]
Ubuntu 16.04 "Xenial" (64-bit)
Instructions for Installing PyRosetta on Windows 10
PyRosetta Binaries in Git repositories use this if you want to frequently update PyRosetta version. (To upgrade simply run 'git pull' on checked out repository. Please note that Git history automatically truncated to store only ~2 last revisions to save disk space.)
To checkout repository with PyRosetta binaries use following command line (replacing 'login' with your user name):
% git clone http://login@git-repository-address
So for example Mac command line will be:
% git clone http://email@example.com/download/PyRosetta4/git/release/PyRosetta4.Release.python27.mac.release.git
In order to update these repositories, you must use:
% git fetch && git reset --hard origin/master && git clean -fd
For a full list of available git repositories please see: [PyRosetta-4, Git repositories] (you will need to enter your user name and password to access this page)
Binaries for older PyRosetta releases could be downloaded here: [PyRosetta3 Download]
PyRosetta is currently only supported on the platforms listed above. Users have sometimes been successful at installing PyRosetta on other platforms; please see the forums for more information, for example, the topic: Building PyRosetta for Linux Mint.